| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P, IF/ICC | 88 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:5000-20000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | FGFR3 Mouse Monoclonal Antibody detects endogenous levels of FGFR3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
FGFR3 also known as CD333, ACH a member of the fibroblast growth factor receptor (FGFR) family, plays a crucial role in regulating cell growth, differentiation, and tissue repair. FGFR-3 is primarily located on the cell surface, where FGFR-3 binds to fibroblast growth factors, initiating a cascade of intracellular signaling that influences cellular processes such as proliferation and survival. Proper functioning of FGFR-3 is vital for normal skeletal development, and mutations in FGFR-3 can lead to a range of skeletal dysplasias, including achondroplasia and thanatophoric dysplasia, highlighting FGFR-3′s importance in human health. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2, 293 cells, using FGFR3 Mouse Monoclonal Antibody (EAB22029) at 1:10000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Predicted band size: 88 kDa; Observed band size: 95-135 kDa  Immunohistochemical analysis of paraffin-embedded Human kidney tissue, using FGFR3 Mouse Monoclonal Antibody (EAB22029) at 1:200 dilution.
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