| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 42 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | DcR2 Rabbit Polyclonal Antibody detects endogenous levels of DcR2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
DcR2 also known as CD264, TNFRSF10D is a member of the TNF-receptor superfamily. DcR2 plays a critical role in modulating apoptosis by acting as a decoy for ligands that typically bind to death receptors, thereby inhibiting apoptotic signaling pathways. This function is particularly significant in cancer, where decoy receptor 2 can contribute to tumor cell survival by preventing apoptosis in response to pro-apoptotic signals. Understanding DcR2 interactions with ligands, such as TRAIL (TNF-related apoptosis-inducing ligand), is essential for elucidating its role in tumorigenesis and developing potential therapeutic strategies. |
| Product Image Gallery | |
 Western blot analysis of extracts on Jurkat, K562 cells, using DcR2 Rabbit Polyclonal Antibody (EAB11338) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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