| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG2b | Monoclonal | WB, IHC-P, IF/ICC, ELISA | 108 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Catenin δ-1 Mouse Monoclonal Antibody detects endogenous levels of Catenin δ-1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Catenin δ-1 also known as delta catenin, catenin delta 1, p120, CTNND1 is a member of the catenin family. Catenin δ-1 plays a crucial role in the regulation of cell adhesion and signaling pathways, particularly in the brain where it interacts with presenilin 1, a protein implicated in Alzheimer′s disease. The presence of catenin δ-1 in the central nervous system highlights its importance in neuronal development and synaptic function. Notably, the gene encoding catenin δ-1 is located on human chromosome 5p15.2, and a hemizygous loss of this gene is associated with Cri-du-Chat syndrome, a genetic disorder characterized by developmental delays and intellectual disability. The interaction of catenin δ-1 with other catenins, such as α-catenin and β-catenin, further emphasizes its role in maintaining cellular integrity and communication. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HEK293, A431 cells, using Catenin δ-1 Mouse Monoclonal Antibody (EAB21895) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human colon tissue, using Catenin δ-1 Mouse Monoclonal Antibody (EAB21895) at 1:200 dilution.
 Immunohistochemical analysis of paraffin-embedded Human pancreas tissue, using Catenin δ-1 Mouse Monoclonal Antibody (EAB21895) at 1:200 dilution.
 Immunohistochemical analysis of paraffin-embedded Human tonsil tissue, using Catenin δ-1 Mouse Monoclonal Antibody (EAB21895) at 1:200 dilution.
|
