| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IF/ICC, FC | 42 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-200 FC=1:10-100 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Basigin/EMMPRIN Rabbit Monoclonal Antibody detects endogenous levels of Basigin/EMMPRIN protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Basigin also known as EMMPRIN, CD147, BSG a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. Basigin also is a member of the immunoglobulin superfamily, ubiquitously expressed in various tissues. Basigin is Basigin plays a crucial role in the regulation of matrix remodeling at the epidermal-dermal interface, where Basigin stimulates fibroblasts to produce various matrix metalloproteinases (MMPs), including interstitial collagenase, gelatinase A, and stromelysin-1. These enzymes are vital during tissue degradation and wound healing, as MMPs facilitate the breakdown of extracellular matrix components, allowing for cellular migration and tissue repair. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Ramos cells, using Basigin/EMMPRIN Rabbit Monoclonal Antibody (EAB21878) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 42 kDa; Observed band size: 42-70 kDa |
