| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IF/ICC, FC | 88 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IP=1:10-100 IF/ICC=1:100-500 FC=1:10-100 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Erk5 Rabbit Monoclonal Antibody detects endogenous levels of Erk5 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Erk5 also known as MAPK7 is a member of the MAP kinase family. Erk5 plays a crucial role in cellular signaling pathways, particularly in regulating gene expression, cell proliferation, and differentiation, which are vital for normal cellular function and response to external stimuli. Erk5 is localized primarily in the nucleus, where Erk5 influences transcriptional regulation by phosphorylating specific transcription factors, thereby modulating the expression of genes involved in cell cycle progression and survival. This nuclear localization enables direct impact on transcriptional machinery and contributes to cellular response to growth factors and stress signals. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela cells, using Erk5 Rabbit Monoclonal Antibody (EAB21819) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 88 kDa; Observed band size: 115 kDa |
