| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IF/ICC | 53 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IRF-6 Rabbit Monoclonal Antibody detects endogenous levels of IRF-6 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IRF-6(Interferon regulatory factor-6) is a member of the interferon regulatory transcription factor (IRF) family. IRF-6 plays a crucial role in regulating gene expression during development, particularly in epidermis formation and palate development. Proper IRF-6 function is essential for preventing congenital defects such as cleft lip and palate, highlighting IRF-6′s importance in developmental biology. Mutations in IRF-6 have been linked to these conditions, underscoring IRF-6′s significance in both normal development and disease. Additionally, IRF-6 interacts with other proteins in the interferon regulatory factor family, which collectively regulate immune responses and cellular growth, further emphasizing IRF-6′s role in maintaining cellular homeostasis and responding to environmental signals. |
| Product Image Gallery | |
 Western blot analysis of extracts on HEK293 cells, using IRF-6 Rabbit Monoclonal Antibody (EAB21786) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 53 kDa; Observed band size: 70 kDa |
