| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 47 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IP=1:10-100 IHC-P=1:50-200 IF/ICC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Caspase-5 Rabbit Monoclonal Antibody detects endogenous levels of Caspase-5 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Caspase-5 also known as CAPS5 is a member of the cysteine-aspartic acid protease (caspase) family. Caspase-5 play a significant role in the inflammatory response by cleaving pro-inflammatory cytokines, thereby facilitating their maturation and release. This function is particularly important in the context of immune responses and tissue homeostasis, as dysregulation of caspase activity can lead to various pathological conditions, including cancer and autoimmune diseases. The human Caspase-5 gene is located on chromosome 11q22.3 and is predominantly expressed in the brain, with notable levels in the lung, liver, and skeletal muscle, highlighting its potential involvement in both central and peripheral immune responses. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela cells, using Caspase-5 Rabbit Monoclonal Antibody (EAB21779)at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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