| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 62 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IP=1:10-100 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | RelB Rabbit Monoclonal Antibody detects endogenous levels of RelB protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
RelB is a crucial member of the NFκB family of transcription factors. RelB playing a significant role in regulating immune responses, inflammation, and cell survival. RelB is primarily located in the nucleus, where RelB forms heterodimers with other NFκB subunits, such as p50, to bind to specific DNA sequences and activate transcription of target genes. Nuclear localization allows RelB to exert effects on gene expression in response to various stimuli, including cytokines and stress signals. RelB heterodimer formation with p50 enhances transcriptional activity, particularly in promoting the expression of genes involved in immune and inflammatory responses. Additionally, RelB undergoes post-translational modifications, such as phosphorylation, which can influence stability and activity, further underscoring RelB importance in cellular signaling pathways. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, NIH/3T3 cells, using RelB Rabbit Polyclonal Antibody (EAB21768) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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