| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC, FC | 23 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-200 IF/ICC=1:100-500 FC=1:10-100 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Rab7 Rabbit Monoclonal Antibody detects endogenous levels of Rab7 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Rab7 plays a crucial role in intracellular transport, particularly in late endosomal and lysosomal pathways, where Rab7 is involved in regulating vesicle trafficking and fusion processes. This function is vital for maintaining cellular homeostasis and facilitating delivery of proteins and lipids to appropriate destinations within cells. Disruptions in Rab7 function have been implicated in various diseases, including neurodegenerative disorders, highlighting Rab7′s importance in cellular health. Rab proteins, including Rab7, are part of the Ras-related superfamily of guanine nucleotide-binding proteins, which exhibit significant homology with Ras p21 and are essential for transport of newly synthesized proteins from endoplasmic reticulum to Golgi apparatus and beyond. Each member of the Rab subfamily is localized to specific stages of membrane transport pathways, underscoring the intricate regulation of cellular transport mechanisms. |
| Product Image Gallery | |
 Western blot analysis of extracts on A431, C2C12 cells, using Rab7 Rabbit Monoclonal Antibody (EAB21758) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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