| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P | 66 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Cytokeratin 1 Rabbit Monoclonal Antibody detects endogenous levels of Cytokeratin 1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Cytokeratin 1 also known as Keratin1, CK1, KRT1 is a member of the keratin gene family. Cytokeratin 1 plays an essential role in the epidermis, constituting a significant portion of keratinocyte cytoskeleton and contributing to skin barrier function. Cytokeratin 1 serves as a key marker for tissue differentiation and helps characterize various malignancies, including epithelioid hemangioendotheliomas, angiosarcomas, schwannomas, epithelioid sarcomas, and synovial sarcomas. Located on chromosome 12q13.13, mutations in the human Cytokeratin 1 gene can lead to abnormal filament associations, resulting in conditions such as epidermolytic hyperkeratosis. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, 293T cells, using Cytokeratin 1 Rabbit Monoclonal Antibody (EAB21714) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 66 kDa; Observed band size: 72 kDa |
