| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC | 58 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Angiopoietin-1 Rabbit Monoclonal Antibody detects endogenous levels of Angiopoietin-1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Angiopoietin-1 also known as ANG-1, ANGPT1 is a secreted glycoprotein that belongs to the angiopoietin family. Angiopoietin-1 plays a vital role in angiogenesis, which is the formation of new blood vessels, and is essential for proper endothelial cell development and function. Angiopoietin-1 is primarily secreted and acts as a ligand for the Tie-2 receptor, which is crucial for vascular stability and integrity. Angiopoietin-1′s interaction with Tie-2 promotes endothelial cell survival and inhibits apoptosis, making Angiopoietin-1 a key player in maintaining vascular homeostasis. Additionally, Angiopoietin-1 has a potential fibrinogen-like domain at its carboxy terminus and coiled-coil regions at the amino terminus, which may influence interactions and functional properties.
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| Product Image Gallery | |
 Western blot analysis of extracts on Hela, C6, Jurkat cells, using Angiopoietin-1 Rabbit Monoclonal Antibody (EAB21684) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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