| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC, FC | 34 | Human, Mouse, Rat, Zebrafish |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IP=1:10-100 IHC-P=1:50-200 IF/ICC=1:50-200 FC=1:10-100 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | hnRNP C1/C2 Rabbit Monoclonal Antibody detects endogenous levels of hnRNP C1/C2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
hnRNP C1/C2 is a member of the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). hnRNP C1/C2 is essential components of the heterogeneous nuclear ribonucleoprotein complexes, playing a critical role in the processing and transport of pre-mRNA. These proteins are primarily located in the nucleus, where they bind to heterogeneous nuclear RNA (hnRNA) produced by RNA polymerase II, facilitating the assembly of spliceosomal complexes necessary for mRNA maturation. The ability of hnRNP C1/ C2 to shuttle between the nucleus and cytoplasm is vital for regulating gene expression, as this movement allows for dynamic response to cellular signals and modulation of mRNA stability and translation. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, MCF7, HepG2 cells, using hnRNP C1/C2 Rabbit Monoclonal Antibody (EAB21688) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 34 kDa; Observed band size: 42 kDa |
