| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC, FC | 122 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IP=1:10-100 IHC-P=1:50-200 IF/ICC=1:50-200 FC=1:10-100 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | MUC1 Rabbit Monoclonal Antibody detects endogenous levels of MUC1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MUC1 also known as Mucin 1, CD227 is a membrane-bound protein that is a member of the mucin family. MUC1 plays a crucial role in cell signaling and adhesion, acting as a protective barrier on epithelial surfaces and influencing tumor progression. MUC1 expression is particularly significant in epithelial tumors, such as breast carcinomas, where Mucin 1 can contribute to tumorigenesis and metastasis. MUC1 is primarily localized to the apical surface of epithelial cells, where MUC1 forms a protective mucosal layer, which is essential for maintaining tissue integrity and function. Understanding the localization and function of MUC1 is vital for developing targeted therapies in cancer treatment, as MUC1 overexpression can serve as a biomarker for malignancy. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, MCF7 cells, using MUC1 Rabbit Monoclonal Antibody (EAB21682) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 122 kDa; Observed band size: 23 kDa |
