| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IF/ICC | 49 | Human, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | FNTB Rabbit Monoclonal Antibody detects endogenous levels of FNTB protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
FNTB also known as FTβ is a 437 amino acid protein containing five PFTB repeats, is responsible for binding peptide substrate, while the α subunit stabilizes the complex with farnesyl pyrophosphate, underscoring the importance of this enzyme in cellular signaling pathways. FNTB protein plays a crucial role in post-translational modification of proteins through farnesylation, a process essential for proper localization and function of several key proteins, including nuclear lamins and oncogene p21Ras. This modification is vital for membrane association of these proteins, influencing their activity and interactions within the cell. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562 cells, using FPTB Rabbit Monoclonal Antibody (EAB21676) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 49 kDa; Observed band size: 43 kDa |
