| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC, FC | 100 | Human, Mouse ,Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IP=1:10-100 IHC-P=1:50-200 IF/ICC=1:50-200 FC=1:10-100 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | αE-Catenin Rabbit Monoclonal Antibody detects endogenous levels of αE-Catenin protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
αE-catenin also known as catenin alpha 1, CTAAN1 is a member of the catenin family of proteins. αE-catenin plays a crucial role in E-cadherin-mediated cell-cell adhesion by linking E-cadherin to the cytoskeleton via interactions with β- or γ-catenin and actin filaments. αE-catenin is essential for maintaining the integrity of adherens junctions, which are vital for tissue architecture and cellular communication. αE-catenin is predominantly located in the neuroepithelial precursor cells of the developing cortical ventricular zone in the brain, where αE-catenin is involved in regulating cell density and the developmental hedgehog signaling pathway. The interactions between αE-catenin and vinculin are particularly important for the assembly of the apical junction complex in epithelial tissues, highlighting αE-catenin′s role in maintaining cellular structure and function. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, A431, HepG2 cells, using αE-Catenin Rabbit Monoclonal Antibody (EAB21621) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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