| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 94 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IP=1:10-100 IHC-P=1:50-200 IF/ICC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | STAT6 Rabbit Monoclonal Antibody detects endogenous levels of STAT6 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Stat6 is a member of the STAT family of transcription factors. Stat6 plays a crucial role in mediating interleukin-4 (IL-4) signaling effects, which are essential for T helper cell differentiation and immune response regulation. Upon IL-4 binding to its receptor, Stat6 undergoes phosphorylation, leading to dimerization and nuclear translocation, where Stat6 activates transcription of genes involved in immune regulation and inflammation. This process is vital for Th2 cell development, which helps combat extracellular pathogens and contributes to allergic responses. Stat6′s ability to modulate gene expression in response to cytokine signaling highlights its importance in both normal immune function and pathological conditions, such as asthma and other allergic diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Raji cells, using Stat6 Rabbit Monoclonal Antibody (EAB21472) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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