| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC | 28 | Human, Mouse, Rat, Zebrafish |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-200 IF/ICC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | BDNF Rabbit Monoclonal Antibody detects endogenous levels of BDNF protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
BDNF is a member of the nerve growth factor family of proteins. BDNF plays a pivotal role in the regulation of neuronal survival, differentiation, and synaptic plasticity, making BDNF essential for brain development and cognitive function. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. BDNF is primarily localized within the secretory pathway of neurons, such as the endoplasmic reticulum and Golgi apparatus, where processing to mature BDNF occurs, a crucial neurotrophin involved in neuronal survival, differentiation, and synaptic plasticity. Understanding the cellular location of BDNF is essential for elucidating its role in neural development and implications in various neurological disorders. |
| Product Image Gallery | |
 Western blot analysis of extracts on A172, Mouse brain cells, using BDNF Rabbit Monoclonal Antibody (EAB21437) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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