| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC | 90 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-200 IF/ICC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TACC3 Rabbit Monoclonal Antibody detects endogenous levels of TACC3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TACC3 also known as ERIC1 is a a member of the transforming acidic coiled-coil (TACC) protein family, plays a crucial role in cell cycle regulation and mitotic spindle assembly, which are essential processes for proper cell division and maintaining genomic stability. TACC3 is primarily localized to the centrosomes and microtubules, where TACC3 is involved in organizing the microtubule network during mitosis. This localization is vital as TACC3 ensures accurate chromosome segregation, preventing aneuploidy, which is often associated with cancer development. TACC3′s interaction with microtubules and centrosomes highlights TACC3′s importance in cellular architecture and function, making TACC3 a significant target for research in cancer biology and therapeutic interventions. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HT29 cells, using TACC3 Rabbit Monoclonal Antibody (EAB21415) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 90 kDa; Observed band size: 140 kDa |
