| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 33 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IP=1:10-100 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | HMOX1/HO-1 Rabbit Monoclonal Antibody detects endogenous levels of HMOX1/HO-1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HO-1(HOxygenase 1) also known as HSP32, HMOX1 plays a crucial role in cellular defense mechanisms by catalyzing the degradation of heme into biliverdin, carbon monoxide, and free iron, thereby contributing to antioxidant protection and cellular homeostasis. The production of carbon monoxide by HO-1 is particularly significant as a signaling molecule in the brain, influencing neurotransmission and vascular regulation. This function is vital for maintaining normal physiological processes and protecting against oxidative stress, which can lead to various pathologies. HO-1 is highly inducible in response to stressors such as heavy metals and oxidative conditions, making HO-1 an important biomarker for studies related to inflammation and cellular stress responses. |
| Product Image Gallery | |
 Western blot analysis of extracts on A549, Mouse spleen cells, using HMOX1/HO-1 Rabbit Monoclonal Antibody (EAB21411) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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