| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC, FC | 16 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-200 IF/ICC=1:100-500 FC=1:10-100 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Survivin Rabbit Monoclonal Antibody detects endogenous levels of Survivin protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Survivin also known as BIRC5 is a member of the inhibitor of apoptosis (IAP) gene family. Survivin plays a crucial role in regulating cell division and inhibiting apoptosis, making survivin a vital component in cancer biology, as survivin overexpression is often associated with tumor progression and resistance to chemotherapy. Survivin is primarily located in the cytoplasm and nucleus of dividing cells, where survivin associates with the mitotic spindle during cell division, ensuring proper chromosomal segregation. Survivin localization is significant because survivin not only contributes to the survival of cancer cells but also serves as a potential biomarker for cancer diagnosis and prognosis. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562, Raji cells, using Survivin Rabbit Monoclonal Antibody (EAB21379) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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