| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF | 45 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IP=1:10-100 IHC-P=1:50-200 IF=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | LAMP2 Rabbit Monoclonal Antibody detects endogenous levels of LAMP2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
LAMP2(Lysosomal associated membrane protein 2) also known as CD107b is a member of a family of membrane glycoproteins. LAMP2 plays a critical role in maintaining lysosomal integrity and acidity, protecting the lysosomal membrane from autodigestion, and facilitating autophagy by mediating the fusion of autophagosomes with lysosomes. LAMP2 is synthesized in the endoplasmic reticulum, sorted at the trans-Golgi network, and trafficked to lysosomes via a pathway distinct from clathrin-coated vesicles. LAMP2 localization to the lysosome is essential for function in cellular homeostasis and the degradation of macromolecules. Dysregulation of LAMP2 expression or function is associated with lysosomal storage disorders, such as Danon disease, and altered expression has been implicated in cancer progression and metastasis. |
| Product Image Gallery | |
 Western blot analysis of extracts on JAR, Human liver cells, using LAMP2 Rabbit Monoclonal Antibody (EAB21324) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 45 kDa; Observed band size: 120 kDa |
