| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, FC | 25 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 FC=1:10-100 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | GAP43 Rabbit Polyclonal Antibody detects endogenous levels of GAP43 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
GAP43(growth associated protein 43) also known as B-50, PP46 is a crucial component for regenerative response in the nervous system. GAP43 plays a vital role in neuronal development and regeneration, being predominantly expressed in growth cones during these processes. GAP43 presence is crucial for axonal outgrowth and synapse formation, which are essential for proper neuronal communication and repair following injury. GAP43 localization in the axonal membrane underscores GAP43′s importance in facilitating dynamic changes required for neuronal plasticity and regeneration. Additionally, GAP43 interacts with specific proteins, such as the neuron-specific Elav/Hu family member HuD, which stabilizes GAP43 mRNA, thereby enhancing protein levels during neuronal development. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse heart, Mouse brain cells, using GAP43 Rabbit Polyclonal Antibody (EAB14772) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 25 kDa; Observed band size: 43 kDa |
