| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 54 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | MMP-3 Rabbit Polyclonal Antibody detects endogenous levels of MMP-3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MMP-3(Matrix metallopeptidase 3) also known as Stromelysin-2 is a member of the matrix metalloproteinase family, which plays a crucial role in the remodeling of the extracellular matrix by degrading various components, including collagen and proteoglycans, which is vital for processes such as tissue repair and development. MMP-3 is particularly important as MMP-3 not only activates procollagenase but also participates in the processing of other MMPs, thereby influencing various physiological and pathological processes, including wound healing, inflammation, and cancer progression. MMP-3 activation is tightly regulated and can occur through two distinct pathways: a slower direct activation by MMP-3 itself and a more rapid activation in conjunction with tissue or plasma proteinases. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7, SW480, HEK293, HepG2 cells, using MMP-3 Rabbit Polyclonal Antibody (EAB11222) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue, using MMP-3 Rabbit Polyclonal Antibody (EAB11222) at 1:100 dilution.
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