Phospho-GATA-4 (Ser262) Rabbit Polyclonal Antibody
Catalog #:EAB14705
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IF/ICC, ELISA 48 Human, Mouse, Rat
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB(Westem Blotting)
IHC-P(Immunohistochemistry-Paraffin)
IF/ICC(Immunofluorescence/Immunocytochemistry)
ELISA(Enzyme-linked Immunosorbent Assay)
WB=1:500-2000 
IF/ICC=1:50-300 
Product Information
Conjugate Unconjugate
Specificity Phospho-GATA-4 (Ser262) Rabbit Polyclonal Antibody detects endogenous levels of GATA-4 protein only when phosphorylated at Ser262.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

P43694

Entrez Gene ID

2626

Product Description

GATA-4 is a member of the GATA family of zinc-finger transcription factors. GATA-4 plays a vital role in cardiac development and function, as GATA-4 is essential for regulating genes involved in heart formation and differentiation. GATA-4 is primarily located in the nucleus, where GATA-4 binds to specific DNA sequences to activate or repress target genes, thereby influencing cardiac tissue development. This nuclear localization enables GATA-4 to interact with other transcription factors and co-regulators, facilitating complex gene expression programs necessary for proper heart development. GATA-4 undergoes post-translational modifications, such as phosphorylation, which can modulate activity and stability, further underscoring GATA-4′s importance in cardiac biology.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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