| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 38 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | XRCC3 Rabbit Polyclonal Antibody detects endogenous levels of XRCC3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
XRCC3 is a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. XRCC3 plays a crucial role in DNA repair processes, specifically in maintaining chromosome stability during cell division. XRCC3 is essential for repairing DNA double-strand breaks through homologous recombination, a process that ensures genetic integrity and prevents genomic instability, which can lead to cancer and other diseases. XRCC3 interacts directly with Rad51, a key protein in homologous recombination repair pathway, facilitating accurate repair of damaged DNA. This interaction is vital for proper functioning of DNA repair machinery, as any defects in XRCC3 or associated proteins can compromise cellular ability to repair DNA, ultimately affecting cell survival and proliferation. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2 cells, using XRCC3 Rabbit Polyclonal Antibody (EAB14644) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry analysis of paraffin-embedded Human lung carcinoma tissue, using XRCC3 Rabbit Polyclonal Antibody (EAB14644) at 1:100 dilution.
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