www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 314 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IP3 Receptor Rabbit Polyclonal Antibody detects endogenous levels of IP3 Receptor protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IP3 receptor also known as IP3R-I, IP3R1, ITPR1 is an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in IP3 receptor cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for IP3 receptor. IP3 receptor functions as a critical intracellular receptor for inositol 1,4,5-trisphosphate (IP3), acting as a calcium release channel that mediates calcium signaling in various cell types. This function is essential for regulating diverse cellular processes, including exocrine secretion, energy metabolism, and neuronal activity, making IP3 receptor a vital component in the central nervous system and liver. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293T cells, using IP3 Receptor Rabbit Polyclonal Antibody (EAB11074) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 314 kDa; Observed band size: 320 kDa  Immunohistochemistry of paraffin-embedded Human brain tissue, using IP3 Receptor Rabbit Polyclonal Antibody (EAB11074) at 1:200 dilution.
|
