| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 42 | Human, Monkey |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Rad51C Rabbit Polyclonal Antibody detects endogenous levels of Rad51C protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Rad51C also known as R51H3, Rad51l2A is a member of the RAD51 family, primarily localized in the nucleus, where Rad51C plays an essential role in the homologous recombination repair pathway responsible for fixing DNA double-strand breaks. This nuclear localization is crucial because Rad51C has direct access to the genomic DNA, facilitating accurate and efficient repair processes that maintain genomic stability and prevent mutations that could lead to cancer. These interactions are essential for orchestrating the homologous recombination machinery, ensuring that DNA breaks are repaired correctly and timely. Additionally, Rad51C collaborates with key proteins like BRCA1 and BRCA2, which are critical for the DNA damage response and repair mechanisms, thereby enhancing the cell′s ability to maintain genomic integrity. |
| Product Image Gallery | |
 Western blot analysis of extracts on COS7 cells, using Rad51C Rabbit Polyclonal Antibody (EAB14631) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 42 kDa; Observed band size: 50 kDa |
