| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 102 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | KSR1 Rabbit Polyclonal Antibody detects endogenous levels of KSR1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
KSR1(Kinase suppressor of ras 1) plays a crucial role in the Ras signaling pathway, which is essential for various cellular processes, including growth, differentiation, and survival. KSR1 is primarily located in the cytoplasm and acts as a scaffold that facilitates the interaction between Ras and Raf-1, thereby promoting the activation of downstream signaling cascades. Proper functioning of KSR1 is vital, as dysregulation of this pathway can lead to various diseases, including cancer. KSR1′s ability to modulate Ras signaling highlights its importance in maintaining cellular homeostasis and underscores the relevance of studying KSR1 in the context of signal transduction research. |
| Product Image Gallery | |
 Western blot analysis of extracts on NIH/3T3 cells, using KSR1 Rabbit Polyclonal Antibody (EAB14566) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 102 kDa; Observed band size: 115 kDa  Immunohistochemistry analysis of paraffin-embedded Human brain tissue, using KSR1 Rabbit Polyclonal Antibody (EAB14566) at 1:100 dilution.
 Immunofluorescence analysis of HuvEc cell, using KSR1 Rabbit Polyclonal Antibody (EAB14566) at 1:100 dilution.
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