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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 49 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-SGK1 (Ser78) Rabbit Polyclonal Antibody detects endogenous levels of SGK1 protein only when phosphorylated at Ser78. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
SGK1 also known as SGK is a serine/threonine protein kinase that plays a crucial role in cellular signaling pathways, particularly in the regulation of ion channels. SGK1 is primarily located in the cytoplasm and is activated in response to growth factors and hormones, which is vital for processes such as cell survival and renal sodium excretion. SGK1′s localization enables interaction with various membrane proteins, thereby influencing their activity and contributing to the maintenance of cellular homeostasis. SGK1 is a downstream target of phosphoinositide 3-kinase signaling, and activation leads to the phosphorylation of key substrates that modulate ion transport and cell proliferation. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293 cells treated with UV, using Phospho-SGK1 (Ser78) Rabbit Polyclonal Antibody (EAB10869) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
Predicted band size: 49 kDa; Observed band size: 54 kDa |
