| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 17 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-Stathmin (Ser16) Rabbit Polyclonal Antibody detects endogenous levels of stathmin protein only when phosphorylated at Ser16. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Op18 also known as oncoprotein 18, stathmin, STMN1 is a highly conserved, tubulin-associated intracellular phosphoprotein that plays a pivotal role in regulating microtubule dynamics. Op18′s ability to modulate microtubule stability is crucial for proper cell division and differentiation, making Op18 an essential player in various cellular processes. Notably, Op18 undergoes multiple post-translational modifications, including phosphorylation, which can significantly influence activity and interactions with other proteins. Such regulation is particularly important in cancer, as aberrant expression and modification of Op18 have been linked to various malignancies, including breast carcinomas and acute leukemias. Op18′s presence in these cancers underscores potential as a biomarker and therapeutic target, highlighting the importance of understanding Op18 function and regulation in both normal and pathological states. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293 cells, using Phospho-Stathmin/Op18 (Ser16) Rabbit Polyclonal Antibody (EAB10814) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
 Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue, using Phospho-Stathmin (Ser16) Rabbit Polyclonal Antibody (EAB10814) at 1:100 dilution.
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