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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 28 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-FADD (Ser194) Rabbit Polyclonal Antibody detects endogenous levels of FADD only when phosphorylated at Ser194 |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
FADD also known as GIG3, MORT1 is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. FADD plays a critical role as an adaptor molecule in the apoptotic signaling pathways initiated by death receptors such as FAS and TNF receptors, facilitating the recruitment and activation of downstream caspases that execute programmed cell death. This function is essential for maintaining cellular homeostasis, regulating immune responses, and preventing uncontrolled cell proliferation, which is vital in cancer research and the study of various autoimmune diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela cells treated with Paclitaxel, using Phospho-FADD (Ser194) Rabbit Polyclonal Antibody (EAB10753) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
 Western blot analysis of extracts on Mouse kidney, Mouse brain, Mouse spleen, Mouse lung cells, using FADD Rabbit Polyclonal Antibody (EAB10753) at 1:500 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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