| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 78 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-Etk/BMX (Tyr40) Rabbit Polyclonal Antibody detects endogenous levels of Etk/BMX only when phosphorylated at Tyr40. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Etk also known as BMX is a member of the Tec family of non-receptor tyrosine kinases, BMX plays a crucial role in cellular signaling pathways that regulate cell growth, differentiation, and survival, particularly in hematopoietic cells. BMX expression is notably high in the heart, where BMX is involved in cardiomyocyte function and response to stress, making BMX essential for maintaining cardiovascular health. BMX protein is structurally characterized by the presence of SH3 and SH2 domains, which facilitate protein-protein interactions, and a Pleckstrin homology domain that aids in membrane localization. Understanding BMX function and regulation is vital, as dysregulation of this kinase has been implicated in various diseases, including cancer and cardiovascular disorders. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2 cells, using Phospho-Etk/BMX (Tyr40) Rabbit Polyclonal Antibody (EAB10746) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
 Immunohistochemistry analysis of paraffin-embedded Human skin tissue, using Phospho-Etk/BMX (Tyr40) Rabbit Polyclonal Antibody (EAB10746) at 1:100 dilution.
 Immunofluorescence analysis of NIH/3T3 cell, using Phospho-Etk/BMX (Tyr40) Rabbit Polyclonal Antibody (EAB10746) at 1:100 dilution.
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