Phospho-DAPP1/BAM32 (Tyr139) Rabbit Polyclonal Antibody
Catalog #:EAB10721
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IHC-P, IF/ICC, ELISA 32 Human, Mouse
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB(Westem Blotting)
IHC-P(Immunohistochemistry-Paraffin)
IF/ICC(Immunofluorescence/Immunocytochemistry)
ELISA(Enzyme-linked Immunosorbent Assay)
WB=1:500-2000 
IHC-P=1:50-300 
IF/ICC=1:50-300 
Product Information
Conjugate Unconjugate
Specificity Phospho-DAPP1/BAM32 (Tyr139) Rabbit Polyclonal Antibody detects endogenous levels of DAPP1/BAM32 protein only when phosphorylated at Tyr139.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

Q9UN19

Entrez Gene ID

27071

Product Description

BAM32 is also known as DAPP1 is a B cell-associated adapter that plays a pivotal role in regulating B cell antigen receptor signaling. BAM32 is primarily located in the cytoplasm but can translocate to the cell membrane upon B cell activation, which is crucial for effective immune responses. BAM32 contains one pleckstrin homology (PH) domain and one Src homology 2 (SH2) domain, allowing BAM32 to interact with phosphoinositides and phospholipase C gamma 2, thereby facilitating downstream signaling pathways. BAM32 is predominantly expressed in the placenta and lung tissues, with additional expression observed in the heart, liver, pancreas, and brain, highlighting BAM32′s importance in various physiological processes.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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