| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 44 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Cdc37 Rabbit Polyclonal Antibody detects endogenous levels of Cdc37 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Cdc37(Cell division cycle 37) is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. Cdc37 plays a crucial role in cell cycle regulation by facilitating the formation of cyclin-dependent kinase 4 (Cdk4) and cyclin D1 complex, essential for G1 to S phase transition. Cdc37 forms a stable complex with heat shock protein 90 (Hsp90), important for stability and function of various client proteins involved in cell cycle regulation. Proper functioning of Cdc37 and associated protein interactions are critical for maintaining cellular homeostasis and preventing uncontrolled cell proliferation, which can lead to cancer. |
| Product Image Gallery | |
 Western blot analysis of extracts on HuvEc, MCF7, COS7 cells, using Cdc37 Rabbit Polyclonal Antibody (EAB10684) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue, using Cdc37 Rabbit Polyclonal Antibody (EAB10684) at 1:100 dilution.
 Immunofluorescence analysis of Hela cell, using Cdc37 Rabbit Polyclonal Antibody (EAB10684) at 1:100 dilution.
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