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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 126 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-Tie2 (Tyr992) Rabbit Polyclonal Antibody detects endogenous levels of Tie2 protein only when phosphorylated at Tyr992. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Tie2 also known as Tek is a receptor tyrosine kinase that plays a crucial role in angiogenesis and vascular stability, making Tie-2 essential for proper blood vessel formation and maintenance. Tie-2 is primarily expressed in endothelial cells and is involved in mediating the effects of angiopoietins, which are key regulators of blood vessel development and remodeling. The interaction between Tie-2 and its ligands is vital for maintaining endothelial cell integrity and preventing vascular leakage, which is particularly important in pathological conditions such as cancer and inflammatory diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293T cells, using Phospho-Tie2 (Tyr992) Rabbit Polyclonal Antibody (EAB10589) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
 Immunohistochemical analysis of paraffin-embedded Human gastric carcinoma tissue, using Phospho-Tie2 (Tyr992) Rabbit Polyclonal Antibody (EAB10589) at 1:200 dilution.
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