| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 92 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-TrkB (Tyr706) Rabbit Polyclonal Antibody detects endogenous levels of TrkB protein only when phosphorylated at Tyr706. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TrkB also known as NTRK2 is a member of the tropomyosin receptor kinase family and serves as a crucial tyrosine kinase receptor for neurotrophic factors including brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3). These interactions are fundamental for the development, maintenance, and function of the central and peripheral nervous systems, playing a vital role in neuronal survival, differentiation, and synaptic plasticity. The activation of TrkB by ligands initiates downstream signaling pathways that regulate essential cellular processes, making TrkB a key player in understanding neurological diseases and developing therapeutic interventions. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293, Mouse brain cells, using Phospho-TrkB (Tyr706) Rabbit Polyclonal Antibody (EAB10579) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
Predicted band size: 92 kDa; Observed band size: 92/145 kDa |
