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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 93 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TGF-β Receptor III Rabbit Polyclonal Antibody detects endogenous levels of TGF-β Receptor III protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TGF-β Receptor III also known as TGFβ RIII, TGFBR3，betaglycan plays a crucial role in transforming growth factor beta signaling pathway, which regulates cell growth, differentiation, and immune responses. TGFβ RIII is primarily located on cell surfaces and captures and presents TGFβ to signaling receptors, enhancing signaling cascades that influence cellular processes. TGFβ RIII functions as a secreted and single-pass type I membrane protein consisting of 850 amino acids, featuring a ZP domain that facilitates interaction with TGFβ ligands. TGFβ RIII undergoes significant post-translational modifications, including glycosaminoglycan group attachment, vital for function and stability. TGFβ RIII gene is located on human chromosome 1p22.2, highlighting evolutionary conservation and importance across species. |
| Product Image Gallery | |
 Western blot analysis of extracts on NIH/3T3, Mouse brain cells, using TGF-β Receptor III Rabbit Polyclonal Antibody (EAB13068) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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