| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IP, IHC-P, IF | All |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IP=1:50-200 IHC-P=1:100-500 IF=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-Serine Mouse Monoclonal Antibody detects endogenous levels of Phospho-Serine protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | N/A |
| Entrez Gene ID | N/A |
| Product Description | |
Phospho-Serine also known as P-Ser plays a crucial role in cellular signaling, as p-Ser serves as a key target for various protein kinases that catalyze the phosphorylation of serine residues. This post-translational modification is vital for regulating numerous cellular processes, including cell growth, differentiation, and apoptosis. Phosphorylation of serine can induce significant conformational changes in proteins, which may enhance or inhibit enzymatic activity and influence interactions with other proteins. Understanding serine phosphorylation dynamics is essential for elucidating complex signaling pathways and can provide insights into various diseases, including cancer and neurodegenerative disorders. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Rat Brain, Mouse Brain cells, using Phospho-Serine Mouse Monoclonal Antibody (EAB13439) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human lung caricnoma tissue, using Phospho-Serine Mouse Monoclonal Antibody (EAB13439) at 1:200 dilution.
 Immunohistochemical analysis of paraffin-embedded Human breast caricnoma tissue, using Phospho-Serine Mouse Monoclonal Antibody (EAB13439) at 1:200 dilution.
|
