| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 101 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | DDR1 Rabbit Polyclonal Antibody detects endogenous levels of DDR1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
DDR1(discoidin domain receptor tyrosine kinase 1) is a member of the receptor tyrosine kinase family. DDR1 plays a crucial role in mediating cellular responses to the extracellular matrix, particularly collagen, which is vital for tissue development and repair. Upon activation by collagen, DDR1 initiates signaling pathways that influence cell adhesion, migration, and proliferation, thereby contributing to processes such as wound healing and fibrosis. DDR1′s function is highlighted by involvement in various pathological conditions, including cancer and fibrotic diseases, where dysregulation of receptor tyrosine kinases can lead to aberrant cellular behavior. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2, CACO2, NIH/3T3 cells, using DDR1 Rabbit Polyclonal Antibody (EAB10458) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 101 kDa; Observed band size: 130 kDa |
