| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IF/ICC, ELISA | 31 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IL-2Rα Rabbit Polyclonal Antibody detects endogenous levels of IL-2Rα protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IL-2Rα also known as CD25, IL2RA plays a crucial role in immune response by serving as a high-affinity receptor for interleukin-2 (IL-2), a key cytokine involved in T cell proliferation and differentiation. IL-2Rα expression on T cells is essential for activation and survival, making IL-2Rα a critical component in immune response regulation. IL-2Rα is primarily located on activated T cell surfaces, where IL-2Rα facilitates IL-2 binding, leading to formation of the high-affinity IL-2 receptor complex when paired with β and γ chains. This complex initiates signaling pathways that promote T cell growth and function, underscoring IL-2Rα′s importance in both adaptive and innate immunity. |
| Product Image Gallery | |
 Western blot analysis of extracts on LOVO, Mouse colon cells, using IL-2Rα Rabbit Polyclonal Antibody (EAB10456) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 31 kDa; Observed band size: 55 kDa  Immunofluorescence analysis of Hela cells, using IL-2Rα Rabbit Polyclonal Antibody (EAB10456) at 1:200 dilution.
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