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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 77 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-PKCβ (Ser661) Rabbit Polyclonal Antibody detects endogenous levels of PKCβ only when phosphorylated at Ser661. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PKCβ also known as PKC beta, PRKCB is a crucial member of the protein kinase C (PKC) family. PKCβ plays a significant role in regulating diverse cellular functions such as cell growth, differentiation, gene expression, and hormone secretion. PKCβ is primarily located in the cytoplasm and translocates to the membrane upon activation, which is essential for its role in signal transduction pathways. This translocation allows PKCβ to interact with various substrates and participate in critical cellular processes, including the modulation of cell survival and apoptosis. Activation of PKCβ is influenced by diacylglycerols and phorbol esters, which bind to PKCβ and promote kinase activity. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela cells treated with Heat shock, using Phospho-PKCβ(Ser661) Rabbit Polyclonal Antibody (EAB10449) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
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