www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 42 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PDGF-D Rabbit Polyclonal Antibody detects endogenous levels of PDGF-D protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PDGF-D also known as IEGF is a member of the platelet-derived growth factor family. PDGF-D plays a crucial role in various biological processes, particularly in the regulation of cell growth and survival, making PDGF-D essential for the development and maintenance of connective tissues. PDGF-D is secreted as a disulphide-linked homodimer known as PDGF-DD, which is activated through limited proteolysis to specifically bind to the PDGFR-β receptor, thereby initiating signaling pathways that influence cellular functions. PDGF-D expression is notably observed in fibroblastic adventitial cells, cultured endothelial cells, and various tumor cell lines, highlighting PDGF-D significance in both normal physiology and pathological conditions. |
| Product Image Gallery | |
 Western blot analysis of extracts on L929 cells, using PDGF-D Rabbit Polyclonal Antibody (EAB10426) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue, using PDGF-D Rabbit Polyclonal Antibody (EAB10426) at 1:100 dilution.
|
