| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 56 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IHC-P=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Akt3 Rabbit Polyclonal Antibody detects endogenous levels of Akt3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Akt3 also known as PKBγ is a member of the serine/threonine kinase Akt family, which plays a crucial role in various cellular processes, including metabolism, cell survival, and growth. One of the key features of Akt3 is its pleckstrin homology domain, which is essential for activation by phosphoinositides. This domain allows Akt3 to translocate to the plasma membrane upon stimulation by growth factors, where Akt3 becomes phosphorylated and activated. Proper functioning of Akt3 is vital for insulin signaling, as Akt3 mediates glucose uptake and glycogen synthesis in response to insulin. Dysregulation of Akt3 has been implicated in various diseases, including cancer and metabolic disorders, making Akt3 an important target for therapeutic intervention. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, NIH/3T3, Mouse brain, Rat brain cells, using Akt3 Rabbit Polyclonal Antibody (EAB13035) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Mouse kidney tissue, using Akt3 Rabbit Polyclonal Antibody (EAB13035) at 1:200 dilution.
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