| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 21 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | VEGF-B Rabbit Polyclonal Antibody detects endogenous levels of VEGF-B protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
VEGF-B also known as VEGF2 is a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. VEGF-B plays a crucial role in angiogenesis, which is the formation of new blood vessels from pre-existing ones, a process that is vital for normal physiological functions as well as for tumor growth and metastasis. VEGF-B is predominantly expressed in heart and skeletal muscle, where VEGF-B promotes endothelial cell survival and migration, thereby facilitating blood vessel formation. Notably, VEGF-B exists in two isoforms, VEGF-B167 and VEGF-B186, which are generated through alternative splicing and may have distinct biological activities. The interaction of VEGF-B with its receptors, particularly Flt-1, is essential for mediating angiogenic effects, making VEGF-B a significant target for therapeutic interventions in diseases characterized by abnormal blood vessel growth, such as cancer. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, 293T, Jurkat cells, using VEGF-B Rabbit Polyclonal Antibody (EAB10293) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human tonsil tissue, using VEGF-B Rabbit Polyclonal Antibody (EAB10293) at 1:200 dilution.
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