| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 44 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TGF-β1 Rabbit Polyclonal Antibody detects endogenous levels of TGF-β1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TGF-β1 also known as TGF beta1, TGFB1 plays a crucial role in regulating various cellular processes, including cell growth, differentiation, and immune responses, making TGFβ1 essential for maintaining tissue homeostasis and mediating healing processes. TGFβ1 is primarily secreted by platelets and various cell types, including macrophages and fibroblasts, and exists in the extracellular matrix, where TGFβ1 influences surrounding cell behavior. TGFβ1′s location in the extracellular space enables interaction with specific receptors on target cells, initiating signaling cascades that lead to diverse biological outcomes, such as fibrosis or immune suppression. Understanding TGFβ1 dynamics and interactions is vital for developing therapeutic strategies for diseases characterized by dysregulated TGFβ signaling, such as cancer and autoimmune disorders. |
| Product Image Gallery | |
 Western blot analysis of extracts on HT29, HepG2, Mouse brain cells, using TGF-β1 Rabbit Polyclonal Antibody (EAB14806) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 44 kDa; Observed band size: 12,25,45 to 65 kDa  Immunohistochemical analysis of paraffin-embedded Human endometrium tissue, using TGF-β1 Rabbit Polyclonal Antibody (EAB14806) diluted at 1:200.
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