| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 37 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-IkBβ (Ser23) Rabbit Polyclonal Antibody detects endogenous levels of IkBβ protein only when phosphorylated at Ser23. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IkBβ also known as IKBB, NFKBIB is a member of the NF-kappa-B inhibitor family. IkBβ plays a crucial role in regulating the NFkB signaling pathway, which controls immune responses, inflammation, and cell survival. By sequestering NF-κB dimers in the cytoplasm, IkBβ prevents their translocation to the nucleus, thereby inhibiting the transcription of target genes involved in these processes. IkBβ′s importance extends beyond regulatory function; post-translational modifications, such as phosphorylation, can influence stability and interaction with NFkB. These modifications are critical for timely activation and resolution of immune responses, highlighting IkBβ′s significance in maintaining cellular homeostasis and responding to various stimuli. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela cells treated with TNFalpha, using Phospho-IkBβ (Ser23) Rabbit Polyclonal Antibody (EAB10046) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
 Immunohistochemistry analysis of paraffin-embedded Human lung carcinoma tissue, using Phospho-IkBβ (Ser23) Rabbit Polyclonal Antibody (EAB10046) at 1:100 dilution.
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