
| Biological Activity | |||||||||||||||||||||||||
| Synonyms | NSC 14613, 4-Pyridinecarboxylicacid, 2-phenylhydrazide | ||||||||||||||||||||||||
| Chemical Name | 4-Pyridinecarboxylic acid 2-phenylhydrazide | ||||||||||||||||||||||||
| Application | PluriSln 1 is a SCD1 inhibitor and apoptosis inducer | ||||||||||||||||||||||||
| CAS Number | 91396-88-2 | ||||||||||||||||||||||||
| Purity | ≥98% | ||||||||||||||||||||||||
| Molecular Weight | 213.24 | ||||||||||||||||||||||||
| Molecular Formula | C₁₂H₁₁N₃O | ||||||||||||||||||||||||
| SMILES | C1=CC=C(C=C1)NNC(=O)C2=CC=NC=C2 | ||||||||||||||||||||||||
| Target & IC50 | SCD | ||||||||||||||||||||||||
| Shipping | Gel Pack | ||||||||||||||||||||||||
| Storage | Store at -20°C | ||||||||||||||||||||||||
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| Solubility | |
| DMSO: 21.3 mg/mL (100 mM)
Ethanol: 21.3 mg/mL (100 mM) |
| Product Description | |
PluriSln 1 a stearoyl-CoA desaturase 1 (SCD1) inhibitor used to selectively eliminate undifferentiated human pluripotent stem cells. It induces apoptosis in hPSCs to the exclusion of differentiated or progenitor cells. It is reported to prevent teratoma formation in immunocompromised mice. |