IDE1 (CAS: 1160927-48-9)
Catalog #:EBC51110
Biological Activity
Synonyms IDE 1, IDE-1, endoderm formation inducer
Chemical Name 2-((E)-((Z)-(6-carboxy-1-hydroxyhexylidene)hydrazono)methyl)benzoic acid
Application IDE1 is an endoderm formation inducer
CAS Number 1160927-48-9
Purity ≥98.0%
Molecular Weight 306.31
Molecular Formula 1160927-48-9
SMILES C1=CC=C(C(=C1)/C=N\NC(=O)CCCCCC(=O)O)C(=O)O
Target & IC50 Induces definitive endoderm formation: EC5050 = 125 nM (ESCs)
Shipping Gel Pack
Storage Store at -20°C
Preparing Stock Solutions Molecular Structure
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 3.2647 ml 16.3233 ml 32.6467 ml
5 mM 0.6529 ml 3.2647 ml 6.5293 ml
10 mM 0.3265 ml 1.6323 ml 3.2647 ml
50 mM 0.0653 ml 0.3265 ml 0.6529 ml
Solubility
DMSO: 30 mg/mL (97.94 mM)
Product Description

IDE1 activates the TGF-beta signaling pathway and induces definitive endoderm formation in human and mouse embryonic stem cells. It is also reported to increase the levels of Nodal expression, induce Smad2 phosphorylation and SOX17 expression. 

For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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