Clozapine N-oxide (CAS: 34233-69-7)
Catalog #:EBC51077
Biological Activity
Synonyms Clozapine (N-oxide), MZA8BK588J, N-Oxyclozapine
Chemical Name 3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine
Application Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration
CAS Number 34233-69-7
Purity ≥99.0%
Molecular Weight 342.82
Molecular Formula C₁₈H₁₉ClN₄O
SMILES CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2O)C=C(C=C4)Cl
Target & IC50 DREADDs
Shipping Gel Pack
Storage Store at -20°C
Preparing Stock Solutions Molecular Structure
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 2.9170 ml 14.5849 ml 29.1698 ml
5 mM 0.5834 ml 2.9170 ml 5.8340 ml
10 mM 0.2917 ml 1.4585 ml 2.9170 ml
50 mM 0.0583 ml 0.2917 ml 0.5834 ml
Solubility
DMSO: 68 mg/mL (198.35 mM)
Ethanol: 8 mg/mL (23.34 mM)
H₂O: 68 mg/mL (198.35 mM)
Product Description

Clozapine N-oxide is a normally biologically inactive metabolite of clozapine that can be used to specifically activate DREAD receptors, engineered G-protein coupled receptors which are activated by otherwise inert drug-like small molecules. Clozapine is metabolized in the liver by the cytochrome P450 system and is a partial agonist of the serotonin receptor.

For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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