| Biological Activity | |||||||||||||||||||||||||
| Synonyms | 4-Hydroxytamoxifen, 4OH-tamoxifen, 4-monohydroxytamoxifen | ||||||||||||||||||||||||
| Chemical Name | (Z)-4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol | ||||||||||||||||||||||||
| Application | (E,Z)-4-Hydroxytamoxifen is a potent and selective estrogen receptor modulator | ||||||||||||||||||||||||
| CAS Number | 68392-35-8 | ||||||||||||||||||||||||
| Purity | ≥98.0% | ||||||||||||||||||||||||
| Molecular Weight | 387.51 | ||||||||||||||||||||||||
| Molecular Formula | C₂₆H₂₉NO₂ | ||||||||||||||||||||||||
| SMILES | OC1=CC=C(/C(C2=CC=C(OCCN(C)C)C=C2)=C(C3=CC=CC=C3)\CC)C=C1 | ||||||||||||||||||||||||
| Target & IC50 | Estrogen receptor | ||||||||||||||||||||||||
| Shipping | Gel Pack | ||||||||||||||||||||||||
| Storage | Store at -20°C | ||||||||||||||||||||||||
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| Solubility | |
| DMSO: 71 mg/mL (183.2 mM) |
| Product Description | |
(E,Z)-4-Hydroxytamoxifen is a modulator of the of the estrogen receptor, with tissue specific agonistic and antagonistic effects. 4-hydroxy Tamoxifen is the active metabolite of tamoxifen that is also generated in the liver by the CYP2D6 enzyme. It exhibits a greater potency than the parent compound and is reported to be cytostatic and prevent cancerous cells from dividing. |
